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Vasculitis profile, ANA, ANA profile, SS-A, SS-B and autoimmune encephalitis profile were negative. Further MRI imaging of spine and orbit revealed no abnormalities. 1) in stark contrast to the MRI brain that was done 4 years back which showed few indistinct scattered foci of altered signal changes in the superficial white matter of parietal lobe (Fig. Magnetic Resonance Imaging (MRI) Brain revealed extensive and scattered altered signal in bilateral superficial and deep white matters including the corpus callosum, iso-intense in T1-weighted image (T1WI), hyper-intense in T2-weighted image (T2WI), T2-fluid-attenuated-inverse-recovery (FLAIR), without any restricted diffusion or enhancement with contrast (Fig. Cerebrospinal fluid (CSF) analysis showed 3 cells, protein- 38 mg/dL (normal: 10–50 mg/dL) glucose- 66 mg/dL (corresponding serum glucose: 90 mg/dL), negative neuroviral-panel (Zoster, Ebstein–Barr, Herpes simplex, cytomegalovirus, adenovirus, enterovirus, coxsackie B virus, and herpes virus 6, Japanese B virus). Routine blood investigations were unrevealing. Neurological examination was unremarkable, apart from gaze evoked nystagmus. There was history of one episode right focal motor seizure with secondary generalization 4 years back, after which the patient was prescribed anti-epileptic drug (AED), however, was self-discontinued after 2 months. Authors herein intend to present a case of 16-year-old adolescent boy with sole manifestation of episodes of focal seizures 4 years apart, finally diagnosed to be a case of MOGAD, which not only boosts the evidence of establishing the possibility of MOG antibody-associated autoimmune epilepsy but also reinforces the importance of unexplained seizure as a clinical phenotype in MOGAD.Ī 16-year-old-male,with no prior co-morbidities, presented with a single episode of sudden facial deviation to left with neck deviation followed by tonic–clonic movement of all limbs with impaired awareness lasting for 5–6 min, with up-rolling of eyeball and frothing from mouth with a post-ictal confusion for 10 min, without any focal neurological deficits (FND). Pathogenesis is still unclear, though Myelin oligodendrocyte (MOG) antibody-associated autoimmune epilepsy may be one of the plausible mechanism underlying. Recently, there are evidences to correlate the presence of such antibodies with seizures, occurring in association with CNS demyelination, or even as isolated phenomena. Studies have revealed that MOGAD presented with seizures or an encephalitis-like illness more commonly than patients with AQP4-positive Neuromyelitis optica spectrum disorder (NMOSD), which is another acquired primary CNS demyelinating disorder having clinical phenotype similarity with MOGAD. MOGAD is a distinct primary CNS demyelinating disorder with seizure and encephalopathy being common manifestations. With the advancement of our understanding about primary demyelinating disorder of central nervous system (CNS) which also includes Myelin oligodendrocyte associated disease (MOGAD), seizure has becomes an integral part of diagnosis. Seizure as presenting manifestation or as an early diagnostic clue in primary demyelinating disorder like MS is rare. This case of an adolescent boy with sole manifestation of episodes of focal seizures 4 years apart, finally diagnosed to be a case of MOGAD, not only boosts the evidence of establishing the possibility of MOG antibody-associated autoimmune epilepsy but also reinforces the importance of unexplained seizure as a clinical phenotype in MOGAD. The patient received steroids and Rituximab therapy without any further recurrence of seizure or any neuro-deficits and gradual improvement in lesion burden in brain imaging. Brain imaging revealed bilateral superficial and deep white matter lesions including the corpus callosum. Neurological examination showed bilateral gaze evoked nystagmus. There was a history of right focal onset motor seizure with secondary generalized tonic–clonic seizure and impaired awareness 4 years ago. Case presentationĪ 16-year-old-male presented with single episode of left focal onset motor seizure with secondary generalization and impaired awareness, without any other focal neurological deficits. Isolated seizure as a manifestation of myelin oligodendrocyte antibody-associated disease (MOGAD) has rarely been reported previously. 7.2.3 works with El Capitan, I now have it and can confirm that it works, and it is downloadable from various sources. No support is or will be available." That's not a literal quote from anybody's website, but a way to handle it. It could be a message like, "This software worked with that OS in 2014, and you're welcome to download it and use it, at your own risk. Still, while I understand what you're saying about there being ways to find it, and the possible "liability" perhaps that might be implied, I can tell you that other software vendors, like Intuit, make available earlier versions of QuickBooks that were at the time compatible with specific operating system versions, and they pretty much are able to leave it at that. I downloaded it, and I concur: 7.2.3 has been working for me (for a day anyway!) with no problems on this installation of El Capitan. That being said, I did find elsewhere in the Forums a link to 7.2.3 which that user (I believe an employee) said worked with El Cap. OS: The iOS, iPadOS, macOS, tvOS, and watchOS versions supported by this version of Xcode for developing, installing, and debugging applications.I appreciate your reply! And I thought of what you said here just after I posted my comment. This is installation image of Mac OS 10.11 El Capitan that was released on september of 2015. SDK: The version of SDKs included in this version of Xcode.Īrchitecture: The architectures supported for development by this version of Xcode. Mac OS, install media, install disc, mac mini, macbook, operating system. Minimum OS Required: The version of macOS required to install this version of Xcode. Minimum requirements and supported SDKs Xcode Version If you already use Office on a PC or iPad, you will find yourself right at home in Office 2016 for Mac. And watchOS apps submitted to the App Store must be built with Xcode 13 and the watchOS 8 SDK. The new versions of Word, Excel, PowerPoint, Outlook, and OneNote provide the best of both worlds for Mac users - the familiar Office experience paired with the best of Mac. IOS and iPadOS apps submitted to the App Store must be built with Xcode 13 and the iOS 15 SDK. Minimum SDK requirements for App Store submissions. To submit your apps, use the latest version of Xcode available on the Mac App Store or, when available, the latest Release Candidate from the Downloads page. Xcode provides an integrated workflow for Apple Developer Program members to prepare and submit apps to the App Store. For details on the latest released versions, including each beta release, view the Xcode release notes. You can also learn about the latest features and capabilities in Xcode. Learning about Xcodeįor step-by-step guidance on how to use Xcode to build, test, and submit apps to the App Store, take a look at Xcode documentation. Apple Developer Program membership is not required. To download Xcode, simply sign in with your Apple ID. The latest beta version and previous versions of Xcode can be downloaded from the Downloads page. The Mac App Store will notify you when an update is available or you can have macOS update automatically as it becomes available. The current release of Xcode is available as a free download from the Mac App Store. This includes macs that have the potential to run El Capitan but have been upgraded to a newer OS. The next section can only be done on a mac that is capable of running El Capitan. Xcode brings user interface design, coding, testing, debugging, and submitting to the App Store into a unified workflow. Go to Download OS and click on OS X El Capitan 10.11 this downloads InstallMacOSX.dmg to your Downloads folder. Xcode is a complete developer toolset for creating apps for Mac, iPhone, iPad, Apple Watch, and Apple TV. Even though it’s an Intel native app, it runs best on Apple silicon under Rosetta 2 emulation, thanks to the sheer horsepower of the M1 and higher. The beefier your processing power, the better performance you’ll get from CrossOver. Each of these handoffs eats up processing power and makes the resulting games run slower and less reliably than they would if coded for the Mac from the get-go. These Vulkan commands must then go through another interpreter, MoltenVK, to run under Apple’s own 3D toolkit, Metal. CrossOver has to pass those commands through an open-source translator called DXVK, which maps them to the open-source Vulkan 3D standard. For instance, Windows games use a set of tools known as DirectX to enable 3D graphics. The path between original Windows code and successful Mac execution isn’t always straight. That database isn’t comprehensive - some titles I’ve personally used under CrossOver aren’t included - but it’s a good place to start when you’re curious about whether a particular app will run there. It’s easier than ever to run apps you’ve already installed, or add new ones.Ĭodeweavers’ database of popular apps and their compatibility, maintained by volunteer testers, is now more directly integrated into the app itself, rather than requiring a separate visit to Codeweavers's web site. Previous versions hid important toggles and features behind poorly designed contextual menus. CrossOver 22 takes its design cues instead from the Mac App Store, putting crucial options in full view. But CrossOver 22’s biggest leap forward lies in its overhauled interface. You can just delete the bottle and start fresh.ĬrossOver 22’s biggest leap forward lies in its overhauled interface.Įach new version of CrossOver offers under-the-hood improvements to help all apps in general and specific titles in particular run better. In the unlikely event that something goes horribly wrong inside a bottle, it won’t affect your larger system. As with containerized software setups like Docker, this makes CrossOver easier and less stressful to use. You can have multiple separate bottles for different apps, or put all the apps you use in a single vessel. It is also possible that the 0.98 inches could be high, but I doubt it: I had briefly run a sprinkler hose at a low setting, but I had moved the gauge out of the way and I turned the water off immediately once the rain started. Runoff from this branch could have added to the total before I moved the gauge four feet to the west for the last two measurements. I noticed on September 13 that the tree had intruded again: the end of one branch was about 10-15 feet over the gauge, or slightly to the east. The metal gauge had been in the same place for several years, but I have moved it in the past year away from a growing tree. Why do I add “more or less”? Because there is uncertainty in the measurements. The final number: 16.37 inches on rain, more or less. I added a conservative 0.2 inches, since this gauge was under trees (marked as 2 on the graph). Fortunately, I have a second rain gauge in my backyard – a plastic gauge that registered about 0.25 inches. I went outside to check our gauge – only to see that it had been knocked over (probably by raccoons). I awoke on the morning of September 15 th and heard reports that up to 2 inches of rain fell overnight. (The lower shows the uncorrected values.)īut the rain hadn’t stopped. The result was 0.38 inches more than my rough estimate from the night before - a storm total of 14.52 inches up to this time. After bailing out five full tubes of rain, I poured the remaining water through the funnel into the tube to a depth of 13.5 inches, spilling a little bit during this process. Were my measurements accurate? On Friday morning, September 13, I took measurement using a more accurate method to compare with my estimates. I recorded measurements to within the nearest quarter inch (see the graph below). With these flaws, the lack of the ten-to-one exaggeration of depth, and some measurements being taken in the dark with a flashlight, my data were only approximate. That evening I found that the bottom of the gauge sagged in the middle, leading to an even deeper measurement than the downtilt side. The gauge tilts slightly, so I took a measurement on the uptilt side and the downtilt side and took an average. On the morning of September 12th, the gauge was so full and heavy, with over seven inches of rain, that I decided to stick a yardstick in the gauge to measure the rain amount, and save pouring into the inner tube for the end of the storm. The funnel and inner tube doesn’t quite fit, so, I leave the gauge open and then pour the rain into the inner tube using the funnel. I inherited it from a weather-observing neighbor who moved away. Thus, each inch in the tube is equivalent to 0.1 inches (a tenth of an inch) of rainfall. The inner tube’s diameter is just small enough to make the depth of rain ten times what it would be in a gauge without the tube and funnel. It has a funnel that deposits rain into an inner tube with a smaller diameter (like this one), but bigger. The gauge is the same type the National Weather Service uses. It’s also about the many possible sources of error when making rain measurements – from old rain gauges to growing trees and even, possibly, inquisitive raccoons.īy Monday morning (September 16), I had measured over 16 inches in our backyard rain gauge from the storm which began September 10. This is the story of my attempts to measure rain during the storm. Which brings us to the questions - How do you measure rain? And how accurate are the measurements? Even though I have done weather research for many years, during this storm I was reminded how hard it is to measure rain accurately. In early September of 2013, the Boulder, Colorado, area had huge amounts of rain. Peggy LeMone is an NCAR Senior Scientist who studies weather and cloud formation. Looking for a place to eat? It's all in Google Maps: browse nearby restaurants, find one you like, check out the dining environment, and even make reservations.Dr. The wonderful world is all around you, waiting for you to discover. Fine navigation and lane guidance will escort you all the way. You don’t have to worry about missing an illegible ramp exit any more. The first step with right direction gets ahead of others in the following steps. Give your drivers and customers the Google Maps experience they know and love with routes that cover 40 million miles of roads in over 200 countries and territories. Whether you’re expanding your ridesharing operations into Australia or deploying a two-wheeler service in India, we’ve got you covered with detailed, high-quality data for urban areas and cities around the globe. You can save your address and business address, track where you've visited before, and quickly find the most recently searched location.ĭeliver great experiences all over the globe Log in to your Google account and enjoy your own Google Maps. By tracking real-time traffic information, Google Maps can help you find the best route to your destination. At Dolphin Mall, there is something for everyone-and at a discounted price, too. Friday's, Starbucks, Latin Grill, Mojito Bar, Kelly's Cajun Grill, Chicken Connection, Cinnabon/Auntie Anne's and Johnny Rockets. How about Burger King, Cheesecake Factory, Haagen-Dazs, Buffalo Wild Wings Grill & Bar, Charcoal's Latin Grill, Charley's Philly Steaks, Chi Chin Ice Cream rolls, T.F.I. There also are several lunch, dinner and snack options for weary shoppers looking for a break. There are many options for shoppers, including Adidas, Nike, Reebok, Under Armour, AnnTaylor, Armani, Ralph Lauren, Perry Ellis, Michael Kors, Karl Lagerfeld, Kay Spade, Gap, J.Crew, H&M, Kay Jewelers, Foot Locker, Famous Footwear, Crocs, Cole Haan, Coach, Tommy Hilfiger, Zales, Victoria's Secret, Puma, Samsung, T-Mobile, Sunglass Hut, Champs Sports, Calvin Klein, Brooks Brothers, Boss and Banana Republic. Two other major attractions are the 19-screen Cobb Theaters in the second level and an 850-seat, 32,000-square-foot Food Court expansion that added five new restaurants, including BRIO Tuscan Grille, Burger & Beer Joint, Kona Grill and Cabo Flats Cantina & Tequila Bar. Open from 10 to 9:30 Monday through Saturday and 11 to 8 on Sunday, it is anchored by Bass Pro Shops, Bloomingdale's, Burlington Coat Factory, Forever 21, Marshall's Home Goods, Old Navy, Ross Dress for Less and Saks Fifth Avenue. Located at 11401 Northwest 12th Street in suburban Sweetwater, west of downtown Miami, where the Dolphin Expressway and the Florida Turnpike intersect, the two-story, 1.4-million-square-foot facility opened in 2001 and is the second largest mall in Miami-Dade County. Beware of this hotel, test the water as soon as you arrive in your room.Dolphin Mall isn't the biggest shopping mall in the Miami area but it is the most popular with over 240 retail outlets, eight name-brand discounters as anchors and plenty of convenient parking. I stayed in Courtyard South Beach last year with no issues. The staff who checked me out didn't even ask me how was my stay or did I try to get a shower this morning. I wasn't offered a free cup of coffee, a cookie, a free bagel, or something off the bill. I spoke to a manager who said the person who would normally repair this problem was not at the hotel and there was nothing he could do. I was exhausted, wrapped in a towel, had unpacked part of my luggage for what I would need and I told the clerk, I am exhausted and just too tired to repack, redress and move. I called the desk again and was told I could move to another room. I called down to the desk, and spoke with a hotel staff member who said let the water run for 5 minutes, it will heat up. Undressed and headed to the shower to discover there was NO HOT WATER. Once I arrived back in the hotel room, I was exhausted and decided to take a shower and go to bed. Came back dropped off the things and headed across the parking lot to the Dolphin Mall for one other item and dinner. After checking in, I dropped my luggage in the room and headed out in a Lyft to pick up a few things I forgot. I arrived at the hotel earlier than the check-in time and was allowed to check in. Most of the hotels near the Port of Miami were sold out and traffic was terrible. There was a Music Festival in Miami so I didn't get the South Beach Courtyard Marriott that I desired. I booked this hotel for an overnight stay before a Cruise.
He writes that it is “because they trust” in God that God “will keep in perfect peace those whose minds are steadfast”. So, Isaiah urges readers to trust in God. God is willing to redeem and restore, and his perfect peace enters the souls of all who decide to trust him. Although people may sometimes be faithless toward God, God will always be faithful to his people, Isaiah emphasizes. Isaiah predicts that God will save people from their sins. Isaiah sings about how Israel will be judged for their sins yet also restored by God, in his mercy. Isaiah 26:3 is part of a song of praise in which the biblical prophet Isaiah celebrates God’s trustworthiness to provide all that people need, including their ultimate need: salvation. What Is the Context and Background of Isaiah 26:3? For through him we both have access to the Father by one Spirit.” Ephesians 2:14 says about Jesus: “For he himself is our peace” and Ephesians 2:17-18 points out that, “He came and preached peace to you who were far away and peace to those who were near. Trusting God involves being at peace with God through Jesus Christ since Jesus made it possible for all humanity to have relationships with God. Thankfully, God is willing to give that perfect peace to everyone who decides to trust him to provide it. God, who alone is perfect, is the only reliable source of peace. However, only God can actually provide complete and lasting peace. Good circumstances may help you enjoy a temporary feeling of peace. Some people chase after peace of mind from worldly achievements, such as through wealth. As a result of choosing to trust God, you welcome God’s peace into your mind. That means you can enjoy a state of perfect peace as long as you focus your mind from beyond your circumstances to God, and trust him to help you no matter what. What Does 'He Will Keep in Perfect Peace' Mean?Įveryone who chooses to keep their minds steadfast because they trust in God can count on experiencing perfect peace while they do so, according to this verse. In Isaiah 26:3, the Bible promises that God “will keep in perfect peace those whose minds are steadfast, because they trust in you.” Here’s what it means to do that, so you can experience peace in any situation. Peace is possible even in our stressful, troubled world. Rats are also trouble if they are too many. Most important in this game is KEEP HOSPITAL SO CLEAN,īecause patients will argue your hospital is dirty (by trashes and womits). If something goes wrong, you will be warned so try fix your problems. Systems around hospital that people have warm. There must be a lot plants that keep patients happy, drink machines for thirsty patients, heat The hospital must look beautiful, clean and warm. If master doctor have surgery skill, then traineers also get surgery skill too. Only master doctor can teach in lessonĪnd it is useful for beginner doctor. Later game, you can build a training room where you can train your doctors. There are many level of doctors, from beginner to master level. Work itself is very hard for doctors too so make sure that staff have a rest room, where they can rest and get back to work. If they feel sad, give some bonus salary or increase their salary. You need make sure that your staff is happy all time, not let them be sad in work. Receptionist mission is only stand in reception desk.ĭuring running your hospital. clean the hospital from trashs and vomits, repair machinerys and water the plants Nurses run the Pharmacy, ward and fracture clinic In this game have many many staffs: Doctors, Nurses, Handyman and Receiptionist. customersīecome very angry easily, vomits everywhere and rats are running around your hospital, too many customers that slow service can kill your ill patients. Everything is getting more difficult and difficult. You will start a campaign, where are 12 maps and it will start from easiest but when futher you will go. You gain money that require for better equiptments and more hospital space for new rooms, pay salary for staffs etc. Build rooms, hire staffs and cure your patients. Theme Hospital is a business simulaton game, where you lead your hospital. I remember my first time at 1997, when I got this game and played this with my sister. "This game was my favorite game from my childhood" - Noif de Bodemloze One surprise was how meat from animal products can be quite rich in phytonutrients, which are the secondary plant compounds with health benefits, such as terpenoids, alkaloids, flavonoids, lignans, phenols, carotenoids, and tocopherols. Grass finished meat is also quite dense in many other nutrients, particularly if the animals were grazed on a pasture that is rich in a diversity of forbs in addition to grasses and legumes. Grass finished ruminant meat, on the other hand, is close to an ideal balance of fatty acid composition. The study did not differentiate between liver from grass finished animals versus grain fed, but in other studies the nutrient density of grass finished ruminants was much higher than that of grain finished, including the content of Omega 3 fatty acids, which are so sorely lacking in the typical American diet. The #1 most nutrient dense food? Hands down, it was liver. What should we be eating? Sara showed studies where different foods were examined and ranked based on nutrient density. The result is that the typical American has an O6:O3 ratio of 15:1 instead of the ideal 1:1. Most of the meat we consume is also highly skewed towards a high ratio of Omega 6 to Omega 3 fatty acids, because what we feed our meat producing animals (primarily corn and soybeans) is very high in Omega 6 fatty acids. Soybean oil has also been strongly correlated to obesity in scientific studies. Soybean oil is also very high in phytoestrogens, which can cause hormonal issues, particularly in young boys. Many vegetable oils are ridiculously high in Omega 6 fatty acids and low in Omega 3 fatty acids, with soybean oil being one of the worst offenders. The typical American diet has an O6:03 ratio of 15:1 which is a long way from the ideal 1:1. But most of the foods we consume are very high in Omega 6 fatty acids and low in Omega 3 fatty acids, and this preponderance of Omega 6 in our diets causes inflammation. We need both O6 and O3 in a healthy diet, but we need them in a balanced ratio close to 1:1. One major consideration of the fats and oils we eat that affects our health is the ratio of Omega 6 to Omega 3 fatty acids. Most vegetable oils, with the exception of coconut oil and avocado oil, undergo drastic changes upon heating which can create carcinogenic compounds. While vegetable oils and margarine were at one time promoted as a healthier alternative to animal fats like lard and butter, we have discovered that they are in fact much worse for us. Sugar and simple starches can cause an overgrowth of Candida yeast in our gut, which can lead to all sorts of health issues, and the yeast actually gives off chemicals that cause us to crave more sugar or starch to keep them fed. Our diet is heavy in sugar, starch and vegetable oils. What is the wrong kind of food? Take a look at the typical American diet. What is becoming increasingly apparent is that most of our major human diseases we fight now (cancer, diabetes, heart disease) are all a direct result of our dietary choices and of how our food is grown, and that was a topic Sara tackled in her talk I was privileged to hear at the 2021 Fuller Field School (Some of Sara’s talk was no surprise at all, such as the basic premise: we eat too much of the wrong kind of food, and too little of the right kinds of food. Recently Sara has been exploring how farming practices affect not only soil health but also how soil health affects the quality of the food we consume, and how those dietary choices affect the trillions of microbes in our gut, and how those microbes affect our health. She now works as a nutrition consultant and is part of the Understanding Ag technical advisor team. Sara has a unique background, in that she earned a degree in biology and worked as a field biologist in wetland preservation before she went back to school and earned a master’s degree in human nutrition. That is my summary of a talk I heard recently given by eco-nutritionist Sara Keough. And when you eat, you aren’t eating for one, you are eating for a trillion, and those trillion eat for you.” “ You are not only what you eat, you are also what you eat has eaten. A Summary of a Sara Keough Talk, Written By: Dale Strickler Go on adventures, take care of pets, manage cafes, and more in these free online games. So what are you waiting for? Whenever you’re looking for great games, just visit girlsgogames. Lots of cute and cool games for girls are here at . The shooting-down of KILLJOY air-launched ballistic missiles, which Vladimir Putin has described as 'undefeatable', will be a 'surprise and an embarrassment' for the Russian president. You can play makeover games, romantic games, Friv games, puzzle games, Bejeweled games, bubble shooter games, and even perform surgery in our medical simulation games. 2) What you need is on mega.nz, but your browser might need the MEGA app to download everything. There’s all sorts of fun waiting for you in GGG Games’ collection of awesome online games for girls. First Guide 1) Ensure you have 7zip installed to decompress the image archives. There’s also tons of craziness and challenges that you’ll find in other popular games like Princesses: Truth or Dare and Poptropica. In those games, you can team up with a toddler named Hazel while she works in her garden, celebrates holidays, and even goes to the dentist. The Baby Hazel series is incredibly popular. If you’d rather babysit a terrific tyke instead of a cat or a dog, try one of the baby games. There’s plenty of adorable creatures, both big and small, that you can feed, groom, and play with in our animal games. If you’ve ever dreamed of working in a hair salon, you can help lots of customers choose the perfect styles in our hair games. Handcraft your very own anime-inspired stories in Gacha Life by Lunime, now playable on now.gg. Play Gacha Life online for free with now.gg mobile cloud. There are many more interesting online games that you can explore here. Welcome to, one of the best websites for the cutest and coolest online games in the entire world! Whether you love taking care of horses, making yummy meals, or managing your very own virtual boutique, you can participate in all of those activities in our always growing collection of online games for girls.Īlso known as GGG, it’s packed full of unicorn games, coloring games, and so much more! You can work on your culinary skills in our cooking games or create outfits that are stylish or completely outrageous in our dress-up games and design games. Gacha Life is a simulation game developed by Lunime and now.gg allows playing game online in your browser. |